Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain
نویسندگان
چکیده
منابع مشابه
The brain needs interleukin-6 (IL-6) to maintain a "healthy" energy balance. Focus on "IL-6 ameliorates defective leptin sensitivity in DIO ventromedial hypothalamic nucleus neurons".
LARSEN AND COLLEAGUES’ (13) recent paper provides an important piece of evidence that leptin sensitivity is under dynamic control and that interleukin-6 (IL-6) is an important player in this control system. IL-6 may increase leptin sensitivity in the ventromedial hypothalamic nucleus (VMN) at least in part by modifying leptin receptor transport to the cell membrane in VMN neurons. This will hel...
متن کاملThe brain needs interleukin - 6 ( IL - 6 ) to maintain a “ healthy ” energy balance 1 2 Focus on “ IL - 6 ameliorates defective leptin sensitivity in DIO ventromedial hypothalamic 3
The brain needs interleukin-6 (IL-6) to maintain a “healthy” energy balance 1 2 Focus on “IL-6 ameliorates defective leptin sensitivity in DIO ventromedial hypothalamic 3 nucleus neurons” 4 5 6 Thomas A. Lutz 7 Institute of Veterinary Physiology and 8 Center of Integrative Human Physiology (ZIHP) 9 University of Zurich 10 Winterthurerstrasse 260 11 8057 Zurich 12 Switzerland 13 14 phone + 41 – ...
متن کاملBrain IL-6 and autism.
Autism is a severe neurodevelopmental disorder characterized by impairments in social interaction, deficits in verbal and non-verbal communication, and repetitive behavior and restricted interests. Emerging evidence suggests that aberrant neuroimmune responses may contribute to phenotypic deficits and could be appropriate targets for pharmacologic intervention. Interleukin (IL)-6, one of the mo...
متن کاملDetection of Interleukin-19 mRNA in C57BL/6 Mice Astroglial Cells and Brain Cortex
Introduction: Astrocytes are the most abundant glial cell type. In addition to their neurological roles, astrocytes also have immune functions. They have been involved in antigen presentation in the central nervous system (CNS). Activated astrocytes express adhesion molecules, chemokines and release several inflammatory mediators, pro-inflammatory cytokines, neurotrophic and neuroprotective fac...
متن کاملP 14: CSF NGF/IL-6 Ratio: a Useful Marker for the Evaluation of Progesterone Efficacy in Traumatic Brain Injury
Introduction: Following our previous studies on the neuroprotective effects of progesterone and cytokines such as IL-6 (IL-6) is involved in the inflammatory response, to examine whether changes in IL-6 and Nerve grows factor(NGF) concentrations in CSF can responsible for the neuroprotective effects of progesterone after traumatic brain injury(TBI). Materials and Methods: Female ovariectomized ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Neuroinflammation
سال: 2012
ISSN: 1742-2094
DOI: 10.1186/1742-2094-9-125